DONDENA Seminar - Bernard Cole
“Racial/Ethnic Mortality Disparities Following Ovarian Cancer Diagnosis: Evaluation of 2009–2018 SEER Data”
SPEAKER: Bernard Cole (University of Vermon)
ABSTRACT:
Prior studies have shown racial/ethnic disparities in mortality among females diagnosed with ovarian cancer; however, most of these studies did not adjust for differences in background mortality. We utilized data from 2009–2018 from the Surveillance, Epidemiology, and End Results (SEER) program of the US National Cancer Institute to assess mortality following ovarian cancer in five race/ethnicity groups: Asian or Pacific Islander, American Indian or Alaska Native, Black, Hispanic White, and Non-Hispanic White. We estimated crude and adjusted (for background mortality, tumor characteristics) mortality rates and determined standardized mortality ratios. This talk presents results obtained from 59,344 ovarian cancer cases meeting eligibility criteria. Included is a discussion of methodological challenges in ascertaining racial/ethnic disparities in cancer outcomes.
BIO:
Bernard F. “Chip” Cole is Professor of Statistics in the Department of Mathematics and Statistics at the University of Vermont (UVM). He previously held faculty appointments at Brown University (1993–1997) and at Dartmouth College (1997–2007), where he was Director of Biostatistics at the Norris Cotton Cancer Center. At UVM, Cole served as dean of the College of Engineering and Mathematical Sciences from 2009 to 2013, and as co-director of the Cancer Control and Population Health Sciences research program at the UVM Cancer Center from 2014 to 2019. Cole’s research focuses on statistical methods in biomedicine, with emphasis on applications to cancer clinical research and epidemiology. His work includes statistical models for quality-of-life-adjusted survival analysis in clinical trials and meta-analysis, methods for longitudinal data analysis in the presence of informative missing information, and the development of methods to ascertain complex treatment-covariate interactions in clinical trials. His applied research activities focus on cancer epidemiology and clinical oncology, including large-scale randomized treatment trials and chemoprevention trials. Cole is an active collaborating biostatistician at the UVM Cancer Center, the International Breast Cancer Study Group, and the National Center for PTSD within the U.S. Department of Veterans Affairs. From 2013 to 2017, Cole served as a voting member of the Oncologic Drugs Advisory Committee of the U.S. Food and Drug Administration. In 2019, Cole became Director of the Vermont Space Grant Consortium and Vermont NASA EPSCoR, where he manages a wide range of programs that support STEM education and NASA-aligned research.
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